HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 59578607, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-Chloropyrimidin-5-amine | HCID 12215993 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59578607 | HCID 59578607 | — |
Reaction Steps
78 μL (0.83 mmol) acetic anhydride are added to 100 mg (0.77 mmol) 2-chloro-pyrimidin-5-ylamine in 20 mL dichloromethane at 0° C. Subsequently 115 μL TEA are added and stirring is continued for 12 h at rt. After that time, the solvent is removed by evaporation and the residue is washed with water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09006450B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-ce1fb2efe5d14334ba1bcbc5febd3e38 |
| Source note | uspto-grants-2015_04 |