Potassium Carbonate → 3-methyl-4-(methoxyphenyl)-5-phenyl-2(5H)-furanone

Participants

Reaction Steps

This reaction is carried out in the same manner as the reaction in example 4. The difference is that 3-methyl-4-chloride-5-phenyl-2(5H)— furanone (42.0 mg, 0.2 mmol), methoxyphenyl boronic acid (46.5 mg, 97%, 0.3 mmol), palladium acetate (2.3 mg, 0.01 mmol), dicyclohexyl(2,4,6-trimethoxyphenyl)phosphine (7.3 mg, 0.02 mmol), potassium carbonate (82.3 mg, 0.6 mmol) are reacted in 1 mL of toluene at 110° C. for 35 minutes and 3-methyl-4-(methoxyphenyl)-5-phenyl-2(5H)— furanone is obtained. The yield is 100%.

Provenance & Evidence