Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 66889872 | HCID 66889872 | — |
| Solvent | 2-Hydroxyquinoline | HCID 6038 | — |
| Product | HCID 86692647 | HCID 86692647 | 90% |
Reaction Steps
500 mg compound 6 from the previous step was mixed with 100 mg Cu powder and 20 ml quinolone. The mixture was heated at about 220° C. for about 2 hours. After cooling to about room temperature, the mixture was poured into 6 M HCl and extracted by ether 3 times. Compound 7 was dried by anhydrous Na2SO4. The yield was about 90%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09006568B2 |
|---|
| Source dataset | uspto-grants-2015_04 |
|---|
| ORD ID | ord-1843643f27e74715aa264495889d2cfe |
|---|
| Source note | uspto-grants-2015_04 |
|---|
