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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1471302Generated: October 30, 2026

Methanol → HCID 178446053, compound

https://huagongshe.com/reaction/1471302

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantL-LeucineHCID 6106—
ReactantHCID 178480554HCID 178480554—
SolventWaterHCID 962—
ProductHCID 178446053HCID 178446053—

Reaction Steps

Tiotropium bromide (1.9 g) and L-leucine (0.3 g) were dissolved into 60 ml methanol. Water (60 ml) was added and shaken until dissolution occurred. The resultant solution was spray dried according to the parameters outlined below.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09011923B2
Source datasetuspto-grants-2015_04
ORD IDord-6f3ca96593ce4a2e91cc8b6c20b4b318
Source noteuspto-grants-2015_04