HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68724543, compound → HCID 68725039, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68724543 | HCID 68724543 | — |
| Reactant | HCID 68726783 | HCID 68726783 | — |
| Reactant | HCID 178476463 | HCID 178476463 | — |
| Solvent | Methyl t-butylether hexane | HCID 21982663 | — |
| Product | HCID 68725039 | HCID 68725039 | — |
Reaction Steps
Prepared as described in Example 10, from 1-(spiro[4.5]deca-2,6-dien-6-yl)ethanone via 3-hydroxy-1-(spiro[4.5]deca-2,6-dien-6-yl)butan-1-one (LDA, acetaldehyde, THF, 72% after FC (SiO2, hexane/MTBE 1:1); 17% starting material recovered) and subsequent Ac2O/AcONa treatment (35% after FC (SiO2, hexane/MTBE 30:1)). Boiling point: 110° C. (0.08 mbar).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09012391B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-23fbe3618f0745deb5f321fe0fa91316 |
| Source note | uspto-grants-2015_04 |