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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1471433Generated: October 30, 2026

Hydrochloric Acid → HCID 86708889, compound

https://huagongshe.com/reaction/1471433

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTrifluoroacetic acidHCID 6422—
ReactantPotassium HydroxideHCID 14797—
ReactantHCID 86708891HCID 86708891—
SolventMethanolHCID 887—
ProductHCID 86708889HCID 86708889—

Reaction Steps

To a solution of methyl 1-(1-methyl-1H-pyrazol-4-yl)-1H-indole-3-carboxylate, TFA (3.5 mg, 9.48 μmol) in MeOH (95 μl) was added a solution of aq. KOH (33.2 μl, 0.066 mmol, 2 M). The reaction mixture was stirred at RT overnight, then acidified with 1N HCl. The solvent was evaporated under reduced pressure and the residue was dried under vacuum overnight. The title compound was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09012447B2
Source datasetuspto-grants-2015_04
ORD IDord-8ea42ac98f30467f8cb278473db8941c
Source noteuspto-grants-2015_04