Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1472059Generated: October 30, 2026

5-(Dimethylphosphoryl)-2-methoxyaniline → N2-[5-(dimethylphosphoryl)-2-methoxyphenyl]-N4-[2-(propan-2-ylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine-2,4-diamine

https://huagongshe.com/reaction/1472059

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Dimethylphosphoryl)-2-methoxyanilineHCID 67052657—
Reactant2-chloro-N-[2-(propan-2-ylsulfonyl)phenyl]-5-(trifluoromethyl)pyridin-4-amineHCID 86668814—
ProductN2-[5-(dimethylphosphoryl)-2-methoxyphenyl]-N4-[2-(propan-2-ylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine-2,4-diamineHCID 68166194—

Reaction Steps

This compound can be prepared as described in Example 80 by reacting 2-chloro-N-[2-(propan-2-ylsulfonyl)phenyl]-5-(trifluoromethyl)pyridin-4-amine with 5-(Dimethylphosphoryl)-2-methoxyaniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09012462B2
Source datasetuspto-grants-2015_04
ORD IDord-06dfef1790384b95a51d907086c2a5d5
Source noteuspto-grants-2015_04