反应详情

Scheme 3: starting from 2,3-dichloro-6-methoxyquinoline (Intermediate 4) and 4-borono-3-fluorobenzoic acid. An aqueous/EtOAc workup was performed followed by purification by silica gel column (PE/EtOAc=1/1) to give the desired product.

1. customAn aqueous/EtOAc workup was performed followed by purification by silica gel column (PE/EtOAc=1/1)