HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → Methyl 4-(7-methoxyquinolin-3-yl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 4-Methoxycarbonylphenylboronic acid | HCID 2734369 | — |
| Reactant | 3-Bromo-7-methoxyquinoline | HCID 18788548 | — |
| Solvent | Water 1,2-dimethoxyethane | HCID 18180031 | — |
| Product | Methyl 4-(7-methoxyquinolin-3-yl)benzoate | HCID 67974241 | — |
Reaction Steps
Followed Step 1 of Compound IV-1, starting from 4-(methoxycarbonyl)phenylboronic acid and Intermediate 13, and where the base used was Na2CO3, the solvent DME/H2O (8: 2), and the reaction was run at 100° C. for 2 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09012646B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-9852867a2f7b41788aa6ae4ab588e6e9 |
| Source note | uspto-grants-2015_04 |