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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1473199Generated: October 31, 2026

2-(Bromomethyl)-5-(trifluoromethyl)furan → HCID 71534519, compound

https://huagongshe.com/reaction/1473199

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)-5-(trifluoromethyl)furanHCID 2794605—
Reactantmethyl 2-(tert-butoxy)-2-(4-(4-chlorophenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-5-yl)acetateHCID 89463134—
ProductHCID 71534519HCID 71534519—

Reaction Steps

The title compound was prepared in a manner similar to that described in Example 2 from methyl 2-(tert-butoxy)-2-(4-(4-chlorophenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-5-yl)acetate and 2-(bromomethyl)-5-(trifluoromethyl)furan. 1H NMR (400 MHz, CHLOROFORM-d) ppm 7.51-7.61 (m, 1H) 7.39-7.47 (m, 2H) 7.32-7.39 (m, 1H) 7.08-7.15 (m, 1H) 6.65-6.73 (m, 1H) 6.43-6.51 (m, 1H) 5.94-6.00 (m, 1H) 5.75-5.91 (m, 2H) 5.26 (s, 1H) 3.63 (s, 3H) 0.96 (s, 9H); LC/MS (m/z) ES+=537 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09012642B2
Source datasetuspto-grants-2015_04
ORD IDord-8f8541ba21a34469a11c988650366b26
Source noteuspto-grants-2015_04