Trifluoroacetic acid → HCID 86678431, compound

Participants

Reaction Steps

A mixture of 1-tert-Butyl 6-hydrogen (2S)-2-[(tert-butoxycarbonyl)amino]-5-(3-fluoropropyl)-hexanedioate (57.0 mg, 0.15 mmol) and trifluoroacetic acid (0.5 mL) and dichloromethane (0.5 mL) was stirred at r.t. for 30 min. Then the mixture was concentrated under reduced pressure and the residue was purified by preparative HPLC (ZIC HILIC, 5 μm 100×4.6 mm, acetonitrile/0.1 M aqueous ammonium formate solution gradient, 10 mL/min).

Provenance & Evidence