反应详情

温度

75 °C

A mixture of imidazo[1,2-a]pyridin-8-ylmethanol (800 mg) and excess thionyl chloride was stirred at 70-80° C. for 8 h. Excess thionyl chloride was removed under vacuum. The residue was then diluted with toluene and evaporated. This procedure was repeated 3 times.

1. customExcess thionyl chloride was removed under vacuum
2. additionThe residue was then diluted with toluene
3. customevaporated