Borane → 5-Bromo-3-fluoro-2-(hydroxymethyl)phenol

HRID 147391Notes

Reaction equation

HRID 147391 reaction equation
[BH3:19].[Br:1][c:2]1[cH:3][c:4]([F:13])[c:5]([C:6](=[O:7])[O:8][CH3:9])[c:10]([OH:12])[cH:11]1.[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[O:14]1[CH2:15][CH2:16][CH2:17][CH2:18]1>>[Br:1][c:2]1[cH:3][c:4]([F:13])[c:5]([CH2:6][OH:7])[c:10]([OH:12])[cH:11]1

Participants

4

Reactant 3

HCID 6331BoraneHCID 8028Tetrahydrofuran2×HCID 66886502Methyl 4-bromo-2-fluoro-6-hydroxybenzoate

Product 1

HCID 671557215-Bromo-3-fluoro-2-(hydroxymethyl)phenol

Sources & evidence

ORD record
ord-2284bba7cbb54504aab2672278f9886c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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