HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1474017Generated: November 1, 2026
5-Amino-2-methylphenol → HCID 68488712, compound
https://huagongshe.com/reaction/1474017
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 5-Amino-2-methylphenol | HCID 17818 | — |
| Reactant | 2-Amino-4-chloropyrimidine | HCID 223332 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68488712 | HCID 68488712 | 94% |
Reaction Steps
Following the general procedure for the synthesis of 2-R-5-(heteroaryl-2-ylamino)phenol, 2-amino-4-chloropyrimidine (70 mg, 0.5 mmol) and 5-amino-o-cresol (67 mg, 0.5 mmol) in 10% aqueous EtOH (2 mL) was heated at 90° C. for 18 h. The title compound was obtained in 94% yield a (110 mg) and used for the next step without additional purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09018209B2 |
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| Source dataset | uspto-grants-2015_04 |
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| ORD ID | ord-176e13de12054db983252129b18d9a07 |
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| Source note | uspto-grants-2015_04 |
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