Acetic Anhydride → 2-(3,4-Difluorobenzyloxy)-4-(acetylamino)-5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)-pyrimidine
Reaction equation
[CH3:33][C:34](=[O:35])[O:36][C:37](=[O:38])[CH3:39].[CH3:40][N:41]([c:42]1[cH:43][cH:44][n:45][cH:46][cH:47]1)[CH3:48].[F:1][c:2]1[cH:3][c:4]([CH2:5][O:6][c:7]2[n:8][c:9](-[c:21]3[c:22]([Cl:28])[cH:23][c:24]([Cl:27])[cH:25][cH:26]3)[c:10](-[c:14]3[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]3)[c:11]([NH2:13])[n:12]2)[cH:29][cH:30][c:31]1[F:32]>>[F:1][c:2]1[cH:3][c:4]([CH2:5][O:6][c:7]2[n:8][c:9](-[c:21]3[c:22]([Cl:28])[cH:23][c:24]([Cl:27])[cH:25][cH:26]3)[c:10](-[c:14]3[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]3)[c:11]([NH:13][C:34]([CH3:33])=[O:35])[n:12]2)[cH:29][cH:30][c:31]1[F:32]Participants
4
Sources & evidence
- ORD record
- ord-ad384e685b454f6d94b66984a949e0b0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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