Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | (2-Hydroxyphenyl)acetic acid | HCID 11970 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | Methyl (2-hydroxyphenyl)acetate | HCID 89719 | — |
Reaction Steps
To a solution of (2-hydroxyphenyl)acetic acid (11 g, 72.3 mmol) in 100 mL of MeOH was added SOCl2 (17.2 g, 144.7 mmol) at 0° C. The mixture was stirred at 50° C. overnight. The reaction was concentrated. The residue was purified column chromatography to give methyl (2-hydroxyphenyl)acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09018211B2 |
|---|
| Source dataset | uspto-grants-2015_04 |
|---|
| ORD ID | ord-0ad020bd2b0f42fa9a449c189991380d |
|---|
| Source note | uspto-grants-2015_04 |
|---|
