反应详情

温度

75 °C

(5-Bromo-2-chlorophenyl)methanol (11.37 g, 51.22 mmol) was taken in aqueous HCl (35%) (1.54 L) and stirred at 70-80° C. for 18 h. After completion of the reaction as confirmed by TLC, the reaction mixture was cooled in an ice bath. The precipitate obtained was collected over Buchner filter, washed with water (2×500 mL) and dried in vacuo to afford the title compound (12.2 g, 99%).

1. customAfter completion of the reaction
2. temperaturethe reaction mixture was cooled in an ice bath
3. customThe precipitate obtained
4. customwas collected over Buchner
5. filtrationfilter
6. washwashed with water (2×500 mL)
7. customdried in vacuo