Dimethylformamide → 3-Fluoro-1,3-dihydro-1-methyl-7-chloro-5-phenyl-2H-1,4-benzodiazepin-2-one

HRID 147512Notes

Reaction equation

HRID 147512 reaction equation
[CH3:21][I:22].[F:1][CH:2]1[C:3](=[O:20])[NH:4][c:5]2[c:6]([cH:15][c:16]([Cl:19])[cH:17][cH:18]2)[C:7]([c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)=[N:8]1.[O:23]=[CH:24][N:25]([CH3:26])[CH3:27]>>[F:1][CH:2]1[C:3](=[O:20])[N:4]([CH3:21])[c:5]2[c:6]([cH:15][c:16]([Cl:19])[cH:17][cH:18]2)[C:7]([c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)=[N:8]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 6328Methyl iodideHCID 131259877-Chloro-3-fluoro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Product 1

HCID 126021203-Fluoro-1,3-dihydro-1-methyl-7-chloro-5-phenyl-2H-1,4-benzodiazepin-2-one

Sources & evidence

ORD record
ord-8fa7ed29ad1f4a2a8bab6e7a73267251
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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