Benzyl Bromide → HCID 70982021, compound

HRID 1475395Notes

Reaction equation

HRID 1475395 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]([CH3:12])[C:7](=[O:11])[NH:8]2)=[CH:4][CH:3]=1.[CH2:13](Br)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:13]([C:6]1([CH3:12])[C:5]2[C:9](=[CH:10][C:2]([Cl:1])=[CH:3][CH:4]=2)[NH:8][C:7]1=[O:11])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 82490717HCID 82490717, compound

Product 1

HCID 70982021HCID 70982021, compound

Procedure

The title compound was prepared from 6-chloro-3-methyl-1,3-dihydro-indol-2-one (700 mg) following similar methods to those described in Preparation 185 using benzyl bromide instead of iodomethane to give the title compound (641 mg) as a white solid. MS: [M+H]+=272.

Sources & evidence

ORD record
ord-8751f117d6514869ad5fcf74b525f190
Source dataset
uspto-grants-2015_04
Patent number
US09018214B2

Reaction notes

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