HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 1-(6-Bromo-3-methyl-3-pyridin-2-yl-2,3-dihydro-indol-1-yl)-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 6-bromo-3-methyl-3-pyridin-2-yl-2,3-dihydro-1H-indole | HCID 86724028 | — |
| Product | 1-(6-Bromo-3-methyl-3-pyridin-2-yl-2,3-dihydro-indol-1-yl)-ethanone | HCID 70981622 | — |
Reaction Steps
Following similar methods to those described in Preparation 335 using 6-bromo-3-methyl-3-pyridin-2-yl-2,3-dihydro-1H-indole (1.2 g, 4.1 mmol), acetyl chloride (360 μL, 5 mmol) and TEA (721 μL, 5 mmol) gave the title compound as a pale yellow oil. MS: [M+H]+=331.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09018214B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-b42744f2103c47edbcfbfe272371e95f |
| Source note | uspto-grants-2015_04 |