HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1-(4-Chloro-3-hydroxy-benzoylamino)-cycloheptanecarboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-(3-Acetoxy-4-chloro-benzoylamino)-cycloheptanecarboxylic Acid Methyl Ester | HCID 67170879 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(4-Chloro-3-hydroxy-benzoylamino)-cycloheptanecarboxylic acid methyl ester | HCID 67170384 | 84.6% |
Reaction Steps
The compound of step 2 (400 mg, 1.088 mmol) was dissolved in methanol (3.5 ml), potassium carbonate (3 mg, 0.02 mmol) was added, and the mixture was stirred at room temperature for 6 h and evaporated to dryness to yield the title compound (300 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09018383B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-b83aa1cd4441487eb4b71efc88ed9774 |
| Source note | uspto-grants-2015_04 |