Isobutyryl chloride → HCID 57211324, compound

Participants

Reaction Steps

[(tert-Butoxy)carbonyl]amino 2-methylpropanoate is prepared from isobutyryl chloride and N-tert-butoxycarbonyl hydroxylamine according to Scheme 1 using the method described by Carpino et al. J. Am. Chem. Soc. 1959, 955-957. (6.36 g, 83%), 1H NMR (250 MHz, DMSO-d6) δ ppm 10.51 (1H, br. s.), 2.65 (1H, sept, 7.0 Hz), 1.40 (9H, s), 1.13 (6H, d, 7.0 Hz).

Provenance & Evidence