HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 53240983, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | [(tert-Butoxy)carbonyl]amino 2,2-dimethylpropanoate | HCID 300008 | — |
| Reactant | 2-Methanesulfonylbenzene-1-sulfonyl chloride | HCID 2735178 | — |
| Product | HCID 53240983 | HCID 53240983 | — |
Reaction Steps
tert-Butyl [(2,2-dimethylpropanoyl)oxy]{[2-(methylsulfonyl)phenyl]sulfonyl}carbamate (46) is prepared from 2-methylsulfonylbenzenesulfonyl chloride, sodium hydride and [(tert-butoxy)carbonyl]amino 2,2-dimethylpropanoate according to Scheme 2. (1.5 g, 78%), 1H NMR (250 MHz, DMSO-d6) δ ppm 8.18-8.37 (2H, m), 7.94-8.15 (2H, m), 3.46 (3H, s), 1.30 (9H, s), 1.29 (9H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09018411B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-75d80f516175409c9a19279344826325 |
| Source note | uspto-grants-2015_04 |