Trifluoroacetic acid → HCID 58288214, compound

Participants

Reaction Steps

16.5 mg (33 μmol) of tert-butyl 3-(3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}-4-cyanophenyl)propanoate were dissolved in 1.1 ml of dichloromethane, and 275 μl of trifluoroacetic acid were added. The reaction mixture was stirred at RT for 1.5 h, then diluted with 20 ml of dichloromethane and concentrated under reduced pressure. The residue was dried under high vacuum overnight. This gave 14.8 mg (97% of theory) of the title compound.

Provenance & Evidence