Hydrochloric Acid → HCID 67258926, compound

Participants

Reaction Steps

To a solution of tert-butyl 4-{1-[(1-methyl-1H-1,2,4-triazol-3-yl)methyl]-2,4-dioxo-6-phenyl-1,4-dihydrothieno[3,2-d]pyrimidin-3(2H)-yl}piperidine-1-carboxylate (944 mg, compound B70) in 1,4-dioxane (25 ml) is added a solution of hydrogen chloride in 1,4-dioxane (5.0 ml, 6.8 M). The reaction mixture is stirred for 17 h at RT. The resulting precipitate is filtered off, washed with diethyl ether and dried in vacuo to afford the title compound as a solid.

Provenance & Evidence