HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67259962, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | tert-butyl 4-{1-[(5-ethyl-2H-tetrazol-2-yl)methyl]-2,4-dioxo-6-phenyl-1,4-dihydrothieno[3,2-d]pyrimidin-3(2H)-yl}piperidine-1-carboxylate | HCID 67257980 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 67259962 | HCID 67259962 | — |
Reaction Steps
According to the procedure described for compound B90 tert-butyl 4-{1-[(5-ethyl-2H-tetrazol-2-yl)methyl]-2,4-dioxo-6-phenyl-1,4-dihydrothieno[3,2-d]pyrimidin-3(2H)-yl}piperidine-1-carboxylate (290 mg, compound B75) is reacted with hydrogen chloride in 1,4-dioxane (5.0 ml, 6.8 M) to afford the title compound as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09018175B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-3fef938b0be7428bb2972544a1dd01ae |
| Source note | uspto-grants-2015_04 |