HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 147716Generated: October 27, 2026
Tetrahydrofuran → 5-(4-Hydroxy-1-methyl-piperidin-4-yl)-1,3-dihydroisoindole-2-carboxylic acid tert-butyl ester
https://huagongshe.com/reaction/147716
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 1-Methyl-4-piperidone | HCID 74049 | — |
| Reactant | N-Boc-5-bromoisoindoline | HCID 16102683 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | 5-(4-Hydroxy-1-methyl-piperidin-4-yl)-1,3-dihydroisoindole-2-carboxylic acid tert-butyl ester | HCID 66672344 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
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| ORD ID | ord-5442cd64ba1c4614a9d84308f9dfbe2d |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
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