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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 14772Generated: October 25, 2026

4-Pyridineethanamine → N-(3-(2-chloropyrimidin-4-yl)benzyl)-2-(pyridine-4-yl)ethanamine

https://huagongshe.com/reaction/14772

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PyridineethanamineHCID 83275—
Reactant3-(2-Chloro-pyrimidin-4-yl)-benzaldehydeHCID 24901965—
ProductN-(3-(2-chloropyrimidin-4-yl)benzyl)-2-(pyridine-4-yl)ethanamineHCID 86603257—

Reaction Steps

Intermediate 1 was coupled with 2-pyridin-4-yl-ethylamine following procedure B. LC-MS showed the product had the expected M+H+ of 325.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732444B2
Source datasetuspto-grants-2010_06
ORD IDord-850b7026eb1e4b538480ecbe00de5cfe
Source noteuspto-grants-2010_06