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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 147732Generated: November 1, 2026

Water → 8-(6-Fluoropyridin-3-yl)-1,4-dioxaspiro[4.5]decan-8-ol

https://huagongshe.com/reaction/147732

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantN,N,N',N'-TetramethylethylenediamineHCID 8037—
Reactant1,4-Dioxaspiro[4.5]decan-8-oneHCID 567415—
Reactant5-Bromo-2-fluoropyridineHCID 2783168—
ReactantButyllithiumHCID 178418339—
Product8-(6-Fluoropyridin-3-yl)-1,4-dioxaspiro[4.5]decan-8-olHCID 59556047—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-5818c6bd15104c3bbdcd4b705181c17b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)