Water → 8-(6-Fluoropyridin-3-yl)-1,4-dioxaspiro[4.5]decan-8-ol
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([F:8])[n:6][cH:7]1.[CH2:22]1[CH2:23][O:24][C:25]2([CH2:26][CH2:27][C:28](=[O:31])[CH2:29][CH2:30]2)[O:32]1.[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH2:9]([Li:10])[CH2:11][CH2:12][CH3:13].[CH3:14][N:15]([CH3:16])[CH2:17][CH2:18][N:19]([CH3:20])[CH3:21].[OH2:38]>>[c:2]1([C:28]2([OH:31])[CH2:27][CH2:26][C:25]3([O:24][CH2:23][CH2:22][O:32]3)[CH2:30][CH2:29]2)[cH:3][cH:4][c:5]([F:8])[n:6][cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-5818c6bd15104c3bbdcd4b705181c17b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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