6-Chloro-4-[4-(4-chlorophenyl)-4-hydroxy-piperidin-1-yl]-1,3,5-triazin-2(1H)-one → HCID 178517888, compound

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Reaction Steps

6-Chloro-4-[4-(4-chlorophenyl)-4-hydroxy-piperidin-1-yl]-1,3,5-triazin-2(1H)-one (341 mg, 1.00 mmol) synthesized in Reference Synthesis Example 21 and palladium hydroxide-activated carbon catalyst (34.1 mg) were used to obtain a mixture of compounds of Reference Synthesis Example 22a and Reference Synthesis Example 22b being the title compounds (424 mg, quantitative) by synthesis in a similar manner to Reference Synthesis Example 3.

Provenance & Evidence