反应详情

A mixture (100 mg) of 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-1,3,5-triazin-2(1H)-one synthesized in Reference Synthesis Example 22a and 4-(4-hydroxy-4-phenylpiperidin-1-yl)-1,3,5-triazin-2(1H)-one, [5-(trifluoromethyl)thiophen-2-yl]methyl 4-methylbenzenesulfonate (558 mg, 0.65 mmol) synthesized in Reference Synthesis Example 51, and potassium carbonate (180 mg, 1.30 mmol) were used to obtain a mixture of compounds in Reference Synthesis Examples 92a and 92b being the title compounds (21 mg) by synthesis in a similar manner to Reference Synthesis Example 91.

1. customto obtain
2. additiona mixture of compounds
3. customby synthesis in a similar manner
4. customto Reference Synthesis Example 91