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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1477620Generated: October 31, 2026

HCID 84681537, compound → HCID 117839585, compound

https://huagongshe.com/reaction/1477620

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 84681537HCID 84681537—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 117839585HCID 11783958552.4%

Reaction Steps

To an ethanol solution (1.0 mL) of [2-(trifluoromethyl)benzofuran-5-yl]methanol (30.0 mg, 0.139 mmol) synthesized in Reference Synthesis Example 96, palladium-activated carbon (15.0 mg) was added and the resultant solution was stirred under hydrogen atmosphere at room temperature for 30 hours. After completion of the reaction, the reaction solution was filtered with Celite and the filtrate was concentrated under reduced pressure to obtain a crude product of the title compound (15.9 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09403798B2
Source datasetuspto-grants-2016_08
ORD IDord-0953faf15d1343e8af781d7d288a7ea4
Source noteuspto-grants-2016_08