HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 84681537, compound → HCID 117839585, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 84681537 | HCID 84681537 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 117839585 | HCID 117839585 | 52.4% |
Reaction Steps
To an ethanol solution (1.0 mL) of [2-(trifluoromethyl)benzofuran-5-yl]methanol (30.0 mg, 0.139 mmol) synthesized in Reference Synthesis Example 96, palladium-activated carbon (15.0 mg) was added and the resultant solution was stirred under hydrogen atmosphere at room temperature for 30 hours. After completion of the reaction, the reaction solution was filtered with Celite and the filtrate was concentrated under reduced pressure to obtain a crude product of the title compound (15.9 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403798B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-0953faf15d1343e8af781d7d288a7ea4 |
| Source note | uspto-grants-2016_08 |