HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Aminopiperidine → 6-(3-Chloro-phenyl)-5-cyclopropyl-pyrazine-2-carboxylic acid piperidin-1-ylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Aminopiperidine | HCID 16658 | — |
| Reactant | 6-(3-Chloro-phenyl)-5-cyclopropyl-pyrazine-2-carboxylic acid | HCID 86682318 | — |
| Product | 6-(3-Chloro-phenyl)-5-cyclopropyl-pyrazine-2-carboxylic acid piperidin-1-ylamide | HCID 71525486 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 6, using 6-(3-chloro-phenyl)-5-cyclopropyl-pyrazine-2-carboxylic acid (Example 3a) and 1-amino-piperidine as starting materials, and isolated (29 mg, 40%) as white solid; LC-MS (UV peak area, ESI) 100%, 357.1485 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403808B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-bc3979ea73b843eb82f6a144f992ac9a |
| Source note | uspto-grants-2016_08 |