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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1477787Generated: November 1, 2026

Methyl L-tert-leucinate hydrochloride → HCID 71525400, compound

https://huagongshe.com/reaction/1477787

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl L-tert-leucinate hydrochlorideHCID 16217630—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acidHCID 86682331—
ProductHCID 71525400HCID 71525400—

Reaction Steps

The title compound was synthesized in analogy to Example 6, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g) and 3-methyl-L-valine methyl ester hydrochloride (1:1) (CAN 63038-27-7) as starting materials, and isolated (98 mg, 91%) as light yellow oil; LC-MS (UV peak area, ESI) 100%, 362.2081 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09403808B2
Source datasetuspto-grants-2016_08
ORD IDord-61fd3ed9cc494992a1e92591f2b46008
Source noteuspto-grants-2016_08