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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1477796Generated: November 1, 2026

Phenylalanine amide hydrochloride → HCID 71525850, compound

https://huagongshe.com/reaction/1477796

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylalanine amide hydrochlorideHCID 11953719—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acidHCID 86682331—
ProductHCID 71525850HCID 71525850—

Reaction Steps

The title compound was synthesized in analogy to Example 15, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g, 100 mg, 0.43 mmol) and (S)-2-amino-3-phenyl-propionamide hydrochloride (1:1) (CAN 5241-58-7, 118.84 mg, 0.64 mmol) as starting materials, and isolated (60 mg, 37.03%) as colorless sticky solid; LC-MS (UV peak area, ESI) 100%, 381.4 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09403808B2
Source datasetuspto-grants-2016_08
ORD IDord-33234379f5464dafbc964238bf62c465
Source noteuspto-grants-2016_08