HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylalanine amide hydrochloride → HCID 71525850, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylalanine amide hydrochloride | HCID 11953719 | — |
| Reactant | 5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid | HCID 86682331 | — |
| Product | HCID 71525850 | HCID 71525850 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 15, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g, 100 mg, 0.43 mmol) and (S)-2-amino-3-phenyl-propionamide hydrochloride (1:1) (CAN 5241-58-7, 118.84 mg, 0.64 mmol) as starting materials, and isolated (60 mg, 37.03%) as colorless sticky solid; LC-MS (UV peak area, ESI) 100%, 381.4 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403808B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-33234379f5464dafbc964238bf62c465 |
| Source note | uspto-grants-2016_08 |