HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-PyridineMethanaMine, a-Methyl-, dihydrochloride, (aS)- → HCID 71525945, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-PyridineMethanaMine, a-Methyl-, dihydrochloride, (aS)- | HCID 53487232 | — |
| Reactant | 5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid | HCID 86682331 | — |
| Product | HCID 71525945 | HCID 71525945 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 15, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g, 100 mg, 0.43 mmol) and (αS)-α-methyl-2-pyridinemethanamine hydrochloride (1:1) (100.0 mg, 0.64 mmol) as starting materials, and isolated (15 mg, 13.03%) as off white solid, LC-MS (UV peak area, ESI) 97.58%, 339.0 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403808B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-bc126242a9014404bf2a3f491545e45d |
| Source note | uspto-grants-2016_08 |