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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1477800Generated: November 3, 2026

2-PyridineMethanaMine, a-Methyl-, dihydrochloride, (aS)- → HCID 71525945, compound

https://huagongshe.com/reaction/1477800

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PyridineMethanaMine, a-Methyl-, dihydrochloride, (aS)-HCID 53487232—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acidHCID 86682331—
ProductHCID 71525945HCID 71525945—

Reaction Steps

The title compound was synthesized in analogy to Example 15, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g, 100 mg, 0.43 mmol) and (αS)-α-methyl-2-pyridinemethanamine hydrochloride (1:1) (100.0 mg, 0.64 mmol) as starting materials, and isolated (15 mg, 13.03%) as off white solid, LC-MS (UV peak area, ESI) 97.58%, 339.0 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09403808B2
Source datasetuspto-grants-2016_08
ORD IDord-bc126242a9014404bf2a3f491545e45d
Source noteuspto-grants-2016_08