HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1S)-2,2,2-Trifluoro-1-(pyridin-2-yl)ethan-1-amine → HCID 71526034, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1S)-2,2,2-Trifluoro-1-(pyridin-2-yl)ethan-1-amine | HCID 26249109 | — |
| Reactant | 5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid | HCID 86682331 | — |
| Product | HCID 71526034 | HCID 71526034 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 6, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g) and (S)-2,2,2-trifluoro-1-pyridin-2-yl-ethylamine (Example 48b) as starting materials, and isolated (71 mg, 85%) as light yellow gum; LC-MS (UV peak area, ESI) 100%, 393.1524 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403808B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-b6ff213f498c429494fed95b5ee13154 |
| Source note | uspto-grants-2016_08 |