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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1477805Generated: November 3, 2026

2-(4-Methyl-1,3-thiazol-2-yl)propan-2-amine → HCID 71526039, compound

https://huagongshe.com/reaction/1477805

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Methyl-1,3-thiazol-2-yl)propan-2-amineHCID 28286206—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acidHCID 86682331—
ProductHCID 71526039HCID 71526039—

Reaction Steps

The title compound was synthesized in analogy to Example 15, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g; 100 mg, 0.42 mmol) and α,α,4-trimethyl-2-thiazolemethanamine (CAN 859466-62-9, 78.2 mg, 0.64 mmol) as starting materials, and isolated (12 mg, 9.22%) as colorless sticky solid, LC-MS (UV peak area, ESI) 99.24%, 373.4 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09403808B2
Source datasetuspto-grants-2016_08
ORD IDord-db15bbc450dc444aaf6231ec4e5391de
Source noteuspto-grants-2016_08