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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1477818Generated: November 1, 2026

HCID 19027559, compound → HCID 71526494, compound

https://huagongshe.com/reaction/1477818

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 19027559HCID 19027559—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acidHCID 86682331—
ProductHCID 71526494HCID 71526494—

Reaction Steps

The title compound was synthesized in analogy to Example 69, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g, 80 mg, 0.34 mmol) and 2-amino-3,N,N-trimethyl-butyramide hydrochloride (CAN 1257848-66-0, 40.1 mg, 0.27 mmol) as starting materials and isolated (35 mg, 28.4%) as white solid; LC-MS (UV peak area, ESI) 93.77%, 361.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09403808B2
Source datasetuspto-grants-2016_08
ORD IDord-6624661959324d22a7221b2bc1da8335
Source noteuspto-grants-2016_08