HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid → HCID 71526580, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid | HCID 86682331 | — |
| Reactant | HCID 86682341 | HCID 86682341 | — |
| Product | HCID 71526580 | HCID 71526580 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 69, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g, 50 mg, 0.21 mmol) and 2-amino-3-cyclobutyl-N-methyl-propionamide (41.2 mg, 0.32 mmol) as starting materials and isolated (20 mg, 25.16%) as white solid; LC-MS (UV peak area, ESI) 99.32%, 373.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09403808B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-0f8b655d2f1c46d4a03fc5c795700016 |
| Source note | uspto-grants-2016_08 |