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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1478066Generated: October 30, 2026

Hydrochloric Acid → HCID 118390062, compound

https://huagongshe.com/reaction/1478066

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthyl AcetateHCID 8857—
ReactantHCID 118390048HCID 118390048—
SolventDichloromethaneHCID 6344—
ProductHCID 118390062HCID 118390062199.4%

Reaction Steps

To a solution of tert-butyl 9-((5-chloro-2-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrimidin-4-yl)amino)-3-azaspiro[5.5]undecane-3-carboxylate (364 mg, 0.7251 mmol) in DCM (10 mL) was added a solution of HCl in ethyl acetate (20 mL, 60 mmol). The reaction was stirred overnight at rt and then concentrated in vacuo to give the title compound as a yellow solid (317 mg, 99%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09403801B2
Source datasetuspto-grants-2016_08
ORD IDord-efc04ad1b63d4615bf0ee8197c06f7c3
Source noteuspto-grants-2016_08