HCID 114685151, compound → HCID 114686176, compound

Participants

Reaction Steps

A mixture of (1-methyl-1H-1,2,3-triazol-5-yl)(1-methyl-1H-imidazol-5-yl)methanol (1.90 g, 9.83 mmol, Intermediate 6: step a) and manganese dioxide (5.04 g, 49.3 mmol) in 1,4-dioxane (100 mL) was stirred in a 100° C. oil bath under argon for 2 hours. The mixture was allowed to cool to room temperature, then was filtered through a pad of Celite®, rinsing with DCM. The filtrate was concentrated, yielding the title compound as a brown powder.

Provenance & Evidence