2-Ethyl-2-(hydroxymethyl)propane-1,3-diol;prop-2-enoic acid → Trimethylolpropane
Reaction equation
C(O)(=O)C=C.C(O)(=O)C=C.C(O)(=O)C=C.[CH2:16]([C:18]([CH2:23][OH:24])([CH2:21][OH:22])[CH2:19][CH3:20])[OH:17]>CO>[CH2:16]([C:18]([CH2:23][OH:24])([CH2:21][OH:22])[CH2:19][CH3:20])[OH:17]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 10 °C
Procedure
The alkylenediamine (ADA for abbreviation) is added into a round-bottom flask equipped with a stirring, a reflux condenser and a thermometer, and cooled to 10° C. below under nitrogen. The methanol solution of trimethylolpropane triacrylate (TMPTA for abbreviation) is then added to the flask, and the mixture is allowed to react at 25˜35° C. for 20˜48 hours, The result solution is subjected to vacuum distillation to remove excess alkylidenediamine (ADA) and methanol at 60˜110° C. for 5˜10 hours to obtain a light-amber viscous material, i.e., intermediate trimethylolpropane core, amino terminated dendrimer (TMPTA-ADA-9NH for abbreviation), wherein a general reaction equation thereof is as follows:
Workup
- customequipped with a stirring, a reflux condenser
- customto react at 25˜35° C. for 20˜48 hours
- distillationThe result solution is subjected to vacuum distillation
- customto remove excess alkylidenediamine (ADA) and methanol at 60˜110° C. for 5˜10 hours
Sources & evidence
- ORD record
- ord-25f49ad63b954a13a1335950cdff06c6
- Source dataset
- uspto-grants-2016_08
- Patent number
- US09403853B2
Reaction notes
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