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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1478796Generated: November 1, 2026

2-Chloro-4-(trifluoromethoxy)aniline → 1-(2-Chloro-4-(trifluoromethoxy)phenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid

https://huagongshe.com/reaction/1478796

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-(trifluoromethoxy)anilineHCID 2734084—
Reactant1-(2-chloro-4-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acidHCID 83662600—
Product1-(2-Chloro-4-(trifluoromethoxy)phenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acidHCID 118513268—

Reaction Steps

The title compound was prepared analogously to 1-(2-chloro-4-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (Example step 2) by replacing 2-chloro-4-methoxyaniline (step 1) with 2-chloro-4-trifluoromethoxyaniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09403833B2
Source datasetuspto-grants-2016_08
ORD IDord-1e3354a1c82344eeb194db71f54bf87c
Source noteuspto-grants-2016_08