Acetic Anhydride → N-(2-bromo-4-chlorophenyl)acetamide

HRID 1478802Notes

Reaction equation

HRID 1478802 reaction equation
[Br:1][C:2]1[CH:8]=[C:7]([Cl:9])[CH:6]=[CH:5][C:3]=1[NH2:4].[C:10](OC(=O)C)(=[O:12])[CH3:11]>>[Br:1][C:2]1[CH:8]=[C:7]([Cl:9])[CH:6]=[CH:5][C:3]=1[NH:4][C:10](=[O:12])[CH3:11]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 701102-Bromo-4-chloroaniline

Product 1

HCID 282685N-(2-bromo-4-chlorophenyl)acetamide

Procedure

A solution of 2-bromo-4-chloroaniline (1 g, 4.84 mmol) in acetic anhydride (5 ml, 4.84 mmol) was stirred at RT for 1.5 hrs. The resulting suspension was collected by filtration and dried on a vacuum line to give the title compound as a white solid.

Workup

  1. filtrationThe resulting suspension was collected by filtration
  2. customdried on a vacuum line

Sources & evidence

ORD record
ord-6c4d328bbaeb4cfb9828bfad7cf44425
Source dataset
uspto-grants-2016_08
Patent number
US09403833B2

Reaction notes

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