Hydrochloric Acid → HCID 23145973, compound

Participants

Reaction Steps

1M NaOH (2 mL; 2 mmol; 4.9 eq.) was added to a solution 2-(1-methyl-piperidin-4-ylidenemethyl)-benzoic acid methyl ester (100 mg; 0.41 mmol; 1 eq.) in EtOH (2 mL) and the reaction mixture was stirred at room temperature for 16 hours. The pH was adjusted to 5 with 1M HCl and the solution was concentrated in vacuo to afford the title compound as a white solid which was used without further purification. HPLC (max plot) 99.1%; Rt 1.69 min.

Provenance & Evidence