Hydrochloric Acid → HCID 89650310, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-(1-methyl-piperidin-4-ylmethyl)-benzoic acid methyl ester (97 mg; 0.39 mmol; 1 eq.) and 5M NaOH (2 mL) in EtOH (3 mL) was stirred at 60° C. for 4 hours. After cooling down, the solution was neutralised with 1M HCl and freeze dried to afford the title compound as a white solid which was used without further purification. HPLC (max plot) 99.8% Rt 1.77 min. UPLC/MS: (MS+) 248.2 ([M+H]+).

Provenance & Evidence