HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-4-(trifluoromethyl)benzoyl chloride → HCID 68372404, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-4-(trifluoromethyl)benzoyl chloride | HCID 145580 | — |
| Reactant | 2-Bromo-1,4-dimethoxy-3-methylnaphthalene | HCID 292240 | — |
| Solvent | Cyclohexane ethylacetate | HCID 21867204 | — |
| Product | HCID 68372404 | HCID 68372404 | — |
Reaction Steps
2-bromo-1.4-dimethoxy-3-methylnaphthalene (300 mg, 1.07 mmol) and commercially available 2-fluoro-4-trifluoromethyl-benzoylchloride (265 mg. 1.17 mmol) were treated according to general procedure 12.1. The resulting yellow oil was purified through flash chromatography (Cyclohexane:EtOAc 10:1). The product was obtained as a yellow oil. Rf(Cyclohexane:EtOAc 10:1)=0.50. Yield=175 mg (42%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409879B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-2e3e679b3c724896baefcd848282073b |
| Source note | uspto-grants-2016_08 |