Dichloromethane → 5-Fluoro-6-methyl-1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one
Reaction equation
[Cl:33][CH2:34][Cl:35].[F:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH:10]3[CH2:11][CH2:12][N:13]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH2:14][CH2:15]3)[c:7](=[O:9])[nH:8]2)[cH:23][c:24]1[CH3:25].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH:10]3[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]3)[c:7](=[O:9])[nH:8]2)[cH:23][c:24]1[CH3:25]Participants
4
Sources & evidence
- ORD record
- ord-a6148d9044c747c5aaf9a39076154420
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…